The keynote presentation, “Sleep and Alzheimer’s Disease: Bi-Directional Relationship with Amyloid-ß and Tau,” by David M. Holtzman, MD, was presented Aug. 27, 2020, during Virtual SLEEP 2020, the 34th annual meeting of the Associated Professional Sleep Societies (APSS). Dr. Holtzman is a professor and chair of neurology at Washington University in St. Louis, where he also is scientific director of the Hope Center for Neurological Disorders and associate director of the Knight Alzheimer Disease Research Center.